NeuroDiol™ high dose CBD Suppository
$69.00 – $269.00
is a unique combination suppository made using a full spectrum hemp extract from an organic Hawaiian grown, high CBD strain, added terpenes, our probiotic blend APO-19, Probiotic strain and (SRT™) slow release technology. NeuroDiol™ Suppositories-Rectal administration of CBD oil allows your body to absorb more CBD than oral consumption? This method bypasses the destructive acids in the stomach and liver delivering the CBD to your bloodstream through the rectal wall. Suppositories are an excellent way to deliver CBD, cannabinoids and terpenes close to problem areas in the rectal and pelvic region such as lower intestines, prostate, vagina and uterus.
NeuroDiol™ comes in 50mg, 125mg, 300mg and 600mg per suppository options. 125mg & 300mg are our best sellers!
is a unique combination suppository made using a full spectrum hemp extract from an organic Hawaiian grown, high CBD strain, added terpenes, our probiotic blend APO-19™ Probiotic strain and (SRT™) slow-release technology. Rectal administration of CBD oil allows your body to absorb more CBD than oral consumption? This method bypasses the destructive acids in the stomach and liver delivering the CBD to your bloodstream through the rectal wall.
Suppositories are an excellent way to deliver CBD close to problem areas in the rectal region such as intestines, prostate, and uterus.
Hemp/CBD Suppositories may be superior to oral or inhalation!
There are many benefits to rectal administration of hemp CBD, even when compared to other methods of hemp/CBD administration. In cases of surgery, illness, or injury, oral methods may not be an option due to vomiting or gastrointestinal difficulties, or physical limitations of the mouth or throat. Orally administration of hemp/CBD undergoes degradation in the gastrointestinal tract and is metabolized by the liver before circulating into the bloodstream. Suppositories are able to bypass these issues and deliver the hemp/CBD into your body more efficiently for a longer sustained effect.
Superior Hemp/CBD Oil Suppositories allow for greater absorption of hemp/CBD than either oral or inhaled methods and the initial effects can be felt in as little as 10-15 minutes after administration, and last for 4-8 hours. There is a great speed of onset and consistency of effect which hemp/CBD suppositories are absorbed by the body makes them a reliable and superior route for many people.
Issues that may impair absorption of hemp CBD from the rectum such as dehydration, whether caused by simply not drinking enough liquid water or by specific medical conditions can greatly reduce suppository absorption. Consult with a medical professional to find what is best for you.
For initial dosing, NeuroDiol should be taken at home and one should not drive after taking it and certainly be careful until you know-how your unique self reacts with Neurodiol™. The effects are typically a mildly relaxed state. One suppository contains the indicated mg of CBD along with the full spectrum of cannabinoids from the whole plant. There is controversy as far as the rectal absorption of the cannabinoids. One just needs to try this route once to know that it does indeed absorb…especially with Glutagenic’s SRT™ and probiotic technology.
Serving size: 1 Servings: 10
Amount Per Piece % Daily Value
CBD from from Hemp & CBD isolate 50mg, 125mg, 300mg & 600mg
Terpenes: Myrcene, Linalool, Lemonene *****
AP0-19™ Probiotic Blend *****
SRT™ Polysaccharide Complex. *****
Daily Value not established****
“I’m one of those guys who often takes oral supplements and notices next to nothing. That’s not uncommon. Digestion, pass through the liver, the acidic nature of the stomach and a host of other factors can keep you from properly absorbing precious molecules. But when I tried Dr. Lieurance’s nasal sprays and suppositories I noticed them almost immediately. I have now used them successfully for jet lag, inflammation and enhanced sleep and I’m completely enamored: these things are the real deal – and a valuable arsenal to any health hacker’s toolkit.”
These are the NON psychoactive components in cannabis. They are the fragrant essence of ALL essential oils! They give plants their unique smell and they also hold the healing benefits within the plants. Terpenes have been studied extensively and they are at the forefront of interest of the pharmaceutical companies due to the unique and safe profile they can have. Terpenes that are specifically shown to reduce pain, are anti inflammatory and reduce anxiety have been incorporated into NeuroDiol™.* These terpenes also have been shown to improve CBD and other cannabinoids utilization and uptake into the brain.*
Myrcene (or β-myrcene) is a terpene that occurs often in highly fragrant plants and herbs such as mangoes, hops, bay laurel leaves, thyme, lemongrass, and basil. Myrcene is produced by numerous cannabis strains, and some rodent-model studies have suggested that it might lend sedative effects. Main effects are Anti-inflammatory, Analgesic (pain relief), Antibiotic, Mood Elevation and Antimutagenic (anti cancer).*
Another place you’ll find myrcene is in mangoes. Anecdotal evidence suggests that eating a ripe mango prior to consuming cannabis may accentuate or extend the effects of cannabinoids; some have suggested that this is due to the fruit’s concentrations of myrcene, which is naturally synergistic with CBD and allows cannabinoids to more easily bridge the blood-brain barrier.
Linalool is a naturally occurring terpene found in many flowers and spices including lavender and coriander. It gives off a complex yet delicate floral aroma, and while its effects are myriad, it is in particular one of the substances used most widely to reduce stress. Humans have inhaled the scent of certain plants, including many containing linalool, since ancient times to help lower stress levels, fight inflammation, and combat depression.* Linalool has been the subject of many studies, including a recent one in which scientists allowed lab rats to inhale linalool while exposing them to stressful conditions. It was reported that linalool returned elevated stress levels in the immune system to near-normal conditions. Linalool’s Effects and Benefits include anti-anxiety, Antidepressant, Mood Elevation, Anti-inflammatory, Anti-epileptic and Analgesic.*
Limonene is an aromatic cannabis terpene produced in the flower’s resin glands. In isolation, it’s commonly associated with fruity and citrus aromas. Inhalation of limonene vapor increases serotonin and dopamine levels in key regions of the brain that are associated with anxiety, depression, and OCD. Limonene’s potential therapeutic benefits have shown potential in the following applications: Elevated mood*, Stress relief*, Antifungal properties*, Antibacterial properties*, May help relieve heartburn and gastric reflux*, Improves absorption of other terpenes and chemicals by way of the skin, mucous membranes, and digestive tract*
There’s also promising evidence for limonene’s anti-tumor effects. In lab rodents, limonene inhibited the growth of skin and mammary tumors. These studies were followed up with a Phase I human clinical trial which found that limonene was somewhat effective at reducing breast cancer tumor growth for nearly a year.* Later studies found that daily limonene supplementation for 2-6 weeks silenced a protein that promotes breast cancer tumor growth, suggesting that daily limonene consumption may inhibit the growth and spread of breast tumors.* Additional reports have revealed benefits of limonene in laboratory models of lung cancer and brain cancer by causing tumor cell death.* But like limonene’s benefits in breast cancer, high doses are likely needed beyond what may be present in cannabis alone. That is why ABC puts large doses into its product in addition to what’s present in its organic hemp extract.
Boswellia, or Indian frankincense, is a resin herbal extract from the boswellia tree, which natural medicine practices have used for centuries. Its anti-inflammatory effects mean that it may help with inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease, and asthma. We included this amazing extract into our products due to all of the positive healing properties
Why Suppository’s makes Sense
Many popped are uneasy with even mentioning of rectal suppositories until they realize how very powerful this approach can prove to be. For some navigating around this phobia could make the difference between health and sickness or enhanced performance fort those biohackers!
There is a growing acknowledgment of the need to provide safer, more cost-effective treatments that can either reduce the need for pharmaceuticals (ie: drugs) and/or to reduce their side effects. There is a mountain of research to demonstrate vitamins, extracts, nutrients, herbals and nutraceuticals can do just that, if only they could be absorbed in such a manner as to allow greater therapeutic effect. Rectal suppositories will provide a level of therapeutic effect on par with an IV at a doctors clinic with a fraction of the cost!
How do Rectal Suppositories Work?
Everything, when administered orally, is absorbed from the gastrointestinal tract into the portal venous circulation and pass through the liver (first pass metabolism) where the process of metabolism or breakdown begins. Suppositories, like intravenous (IV), intramuscular (IM), and transdermal methods of administration, bypass this “first pass” effect and are absorbed into the rectal veins without encountering liver metabolism. Fortunately, the rectum is filled with blood vessels that offer direct access into the body’s bloodstream. This allows for rapid access to systemic circulation.
When nutrients are put into our special suppository base they are protected and delivered through Slow Release Technology along with the support of the probiotics APO-808. All Glutagenic’s™’s proprietary suppository base is formulated with ingredients that promote the movement of the active nutrients from the base to the rectum. This technology facilitates solubility, and allows a compound that is usually insoluble in water (hydrophobic) to dissolve, and thus be absorbed. This is crucial for poorly absorbed compounds.
ABC’s suppositories are easy to insert, non-irritating, rapid-melting, fully absorbed in 5-10 minutes, and you’ll not know its in there after insertion.
Sustained-release technology is ABC’s suppositories are of benefit due to increased bioavailability. ABC has found that the addition of SRT improved the bioavailability of glutathione by 30% compared to the suppositories without SRT. These absorptions were improved enormously by the addition of a proprietary and natural polypeptide. Excellent prolonged absorption and high bioavailability were obtained exhibiting both high plasma level and prolonged absorption. Our research shows that ABC’s preparations containing SRT may be superior in a rectal preparation with prolonged action and giving a high plasma level compared to standard suppository bases without ABC’s SRT!
Why do we use probiotics in our suppositories?
APO-808 is a proprietary blend of probiotic strains that is unique to our suppository technology. ABC has discovered certain bacteria strain combinations of probiotics can support the absorption and utilization when combined with various ingredients. Probiotics are beneficial bacteria that exist in our large intestine as what is called the microbiome, which is exactly where the suppository is absorbed. Using probiotics via suppository makes for a unique route of delivery as it bypasses the acid in the stomach that normally destroys most probiotics taken orally. In addition, it has been clinically shown that oral probiotics may not even colonize your gut at all. Due to the need for probiotics to be incorporated into the gut wall, research has shown we might be wasting our money taking most probiotics orally. ABC’s probiotic strains have been combined with our special suppository base, which consists of organic palm oil. This combination rests on the gut wall over a 5-8 hour period to allow for the incorporation and colonization of the bacteria in the large intestines. Besides the unique delivery of the probiotics via suppository route it has been scientifically shown that many nutrients are brought into the bloodstream by various strains of beneficial flora in your microbiome. The scientists at ABC have isolated various combination of flora that work specifically with the nutrients it is combined with.
APO-808 is designed to work within CBD to down regulate the inflammation through normalizing the gut microbiome as well as allowing maximum absorption of CBD. The strains contained in the APO-808 Blend have been shown in the research to help with the following:
Diarrhea. Including viral diarrhea in children, traveler’s diarrhea, and diarrhea caused by antibiotics, Cancer prevention, Inflammatory bowel disease(IBD, Crohn’s disease, ulcerative colitis), Growth of bacteria in the intestine, Irritable bowel syndrome (IBS), Immune system strengthening. (Helpful in Chronic Lyme, CIRS, and EBV), Digestion problems, Clostridium difficile colitis, Helicobacter pylori infection. Which causes ulcers.
Dosage and Instructions
Dosage and Instructions
Dosage and Storage Instructions: Wash your hands thoroughly with soap and water. Keep the suppository in the refrigerator so it remains hard before removing the wrapper. Put on a finger cot or disposable glove, if desired (available at a pharmacy). Lubricate the suppository with a water soluble lubricant such as K-Y Jelly or coconut oil, not petroleum jelly (Vaseline). If you do not have this lubricant, moisten your rectal area with cool tap water. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Lift upper buttock to expose the rectal area. Insert the suppository, pointed end first, with your finger until it passes the muscular sphincter of the rectum, about ½ to 1 inch in infants and 1 inch in adults (If not inserted past this sphincter, the suppository may pop out). Hold buttocks together for a few seconds. Remain lying down for about 5 minutes to avoid having the suppository come out. Discard used materials and wash your hands thoroughly.
The suggested dosage is 1 (one) suppository daily. Depending on your daily schedule, it is recommended that you insert the suppository prior to bed.
DO NOT DRIVE OR OPERATE MACHINERY AFTER CONSUMING THIS PRODUCT.
Product is not intended for oral usage.
Store this product in a refrigerated climate. Keep this product away from sunlight. Please use the product within six months of the purchase date for best results.
Disclaimer, COA's & Lab Testing
Disclaimer, COA's & Lab Testing
Advanced Biome Corp does not sell or distribute any products that are in violation of the United States Controlled Substances Act (USA CDA). The company does sell and distribute hemp-based products.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent disease or medical conditions. The products and information found on AdvancedBiomeCorp.com are not intended to replace professional medical advice or treatment. Individual results may vary. Advanced Biome Corp urges you to seek the advice of a qualified professional for any health concern, and to share with your provider any information pertaining to your health and well-being, including the use of supplemental nutrition. We try our best not to make mistakes; however, if typographical errors appear on our site, we cannot be held responsible. All information presented here is not meant as a substitute for or alternative to information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice. COA’s and Lab Testing