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NeuroNAD™ Products

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NeuroNAD™ Products. Each suppository contains 500mg of NAD+ and our Nasal Spray contains 2,000 mg. What is NAD? Nicotinamide Adenine Dinucleotide (NAD) is a metabolic co-enzyme that structures, repairs, and is an essential component of energy production (mitochondrial function); heavily involved in DNA repair and cell repair; responsible for turning certain genes on and off; and essential for maintaining neurotransmitter levels, for the proper functioning of the brain.

NeuroNAD™ Suppository contains the finest and highest potency NAD+ along with the following plant based Polyphenols: Fisetin, Ginko Biloba, EGCG, Lutein, Quercitin, Curcumin & Resveratrol. Also the following powerful Terpenes: Alpha Pinene, Beta Pinene, Delta 3 Carene, Alpha Phellandrene. Suppository delivery bypasses the GI tract and delivers NAD+ directly to the bloodstream.

4 OPTIONS FOR PURCHASE:  
1) NeuroNAD™ Nasal Spray in 20ml & 120ml options ( x1)
2) NeuroNAD™ Suppository (x10)
3) Combo-  NeuroNAD™ Suppository x10 & Nasal Spray x1
4) NAD+ Refuel Kit – NeuroNAD™ Suppository x60, Bulk 120ml NeuroNAD Nasal Spray x1,, Resveracel x3.

CONSIDER THE BULK NEURONAD OPTION FOR LONGER PROGRAMS OR TO SHARE WITH YHE ENTIRE FAMILY.  IF YOU HAVE A NEED FOR DIRECTION WITH PRODUCT USE. 

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Description

Description

NeuroNAD™ Products. Each suppository contains 500mg of NAD+ and our Nasal Spray contains 2,000 mg. What is NAD+? Nicotinamide Adenine Dinucleotide (NAD+) is a metabolic co-enzyme that structures, repairs, and is an essential component of energy production (mitochondrial function); heavily involved in DNA repair and cell repair; responsible for turning certain genes on and off; and essential for maintaining neurotransmitter levels, for the proper functioning of the brain.

NeuroNAD™ Suppository contains the finest and highest potency NAD+ along with the following plant based Polyphenols: Fisetin, Ginko Biloba, EGCG, Lutein, Quercitin, Curcumin & Resveratrol. Also the following powerful Terpenes: Alpha Pinene, Beta Pinene, Delta 3 Carene, Alpha Phellandrene. Suppository delivery bypasses the GI tract and delivers NAD+ directly to the bloodstream.

NeuroNAD™ Suppository is a product that was developed with much excitement and care to make sure the blend was perfect. Using a proprietary method to stabilize NAD+ so it is maintained in a suppository using Nano Lipospheric Technology NLT NAD+™.  NeuroNAD™  Suppositories are designed to provide the cleanest and most complete absorption of the NAD+ & Polyphenols through a SRT™ Slow Release Technology along with Nano Lipospheric Technology NLT NAD+™. Some of the most exciting uses of this product are with neurological care, anti-aging, DNA Repair, Promoting Autophagy and Cellular Detox.

The 2 Organs that require the most NAD+ and are also the most sensitive to low levels are the Heart and Brain. The magic of the combination program using both NeuroNAD™ Suppository NeuroNAD™ Nasal Spray is very special.  The NeuroNAD™ Suppository supplies NAD+ directly into the heart via the rectum’s venous drainage and NeuroNAD™ Nasal Spray directly into he brain!  The Science is very special but try them your self and feel the difference.

See the amazing studies on Fisetin you will see why many are looking at this nutrients as the father of all anti aging substances. Take a close look at Micro Glial activation as well as Cellular Senescence to fully appreciate the NeuroNAD™ Suppository & Nasal Spray.

Take a close look at Micro Glial activation as well as Cellular Senescence to fully appreciate NeuroNAD™ Products here.

NAD+ & Polyphenols such as Fisetin are poorly absorbed through oral ingestion. Suppository, can offer a valuable means to receive the most potent and fullest potential of these nutrients.

Multiple studies on NAD+ have been done and currently ongoing for its critical step in the production of energy at the cellular level (ATP production in the mitochondria). Both NeuroNAD™ Suppository & NeuroNAD™ Nasal Spray are both a powerful way to provide NAD+ to your cells as levels decline with age. NeuroNAD™ Suppository & NeuroNAD™ Nasal Spray can be used in combination for an even stronger effect and replenishment.
4 OPTIONS FOR PURCHASE:   
1) NeuroNAD™ Nasal Spray in 20ml & 120ml options ( x1)
2) NeuroNAD™ Suppository (x10)
3) NeuroNAD™Combo-  NeuroNAD™ Suppository x10 & Nasal Spray x1
4) NAD+ Refuel Kit – NeuroNAD™ Suppository x60, Bulk 120ml NeuroNAD Nasal Spray x1, Resveracel x3.

Testimonial

Testimonial

“I’m one of those guys who often takes oral supplements and notices next to nothing. That’s not uncommon. Digestion, pass through the liver, the acidic nature of the stomach and a host of other factors can keep you from properly absorbing precious molecules. But when I tried Dr. Lieurance’s nasal sprays and suppositories I noticed them almost immediately. I have now used them successfully for jet lag, inflammation and enhanced sleep and I’m completely enamored: these things are the real deal – and a valuable arsenal to any health hacker’s toolkit.”

Ben Greenfield

Tips, Tricks and Protocols

Tips, Tricks and Protocols

NeuroNAD™ Suppository and NeuroNAD™ Nasal Spray can be taken together for an even more potent NAD+ replenishment program.The Heart and Brain and the most sensitive to low NAD+ levels. NeuroNAD™ Suppository uses the portal vein to absorb NAD+ directly into the blood stream which circulates directly intl the heart where NeuroNAD™ Nasal Spray is absorbed directly into brain through the nasal mucous. These two routes are the most superior routes next to IV which costs between $500-1500 per IV and the IV’s last 5-8 hours each. NeuroNAD™ Suppository should be taken at night before bed and NeuroNAD™ Nasal Spray should be taken during the daytime 1-4 times a day for a effective boost into the brain where is is most needed!

See NeuroNAD™ Nasal Spray here.

Suppliment Facts

Suppliment Facts

Supplement Facts:

20 milliliters bottle

Contains 30-60 sprays per bottle

Proprietary Blend
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Pure NAD+ Nicotinamide Adenine Dinucleotide      2g/ml
­­­­­­­­­­­­­­­­­­­­­­­­­­­­

Bio Ocean minerals                                                   *mg/ml

Terpenes: Eucalyptol.                                               *mg/ml

Saline                                                                          *mg/ml

Nasal Spray Enhancer Technology                         *mg/ml

*Daily Value not established

Video's on NAD+

Video's on NAD+

Research on NAD+

Research on NAD+

Dr John Lieurance with Dr. Mestayer at the 2015 NAD+ Summit. Dr. Mestayer is considered the leading authority in the USA on intravenous NAD infusions.

What is NAD?

Nicotinamide Adenine Dinucleotide (NAD) is a metabolic co-enzyme that structures, repairs, and is an essential component of energy production (mitochondrial function); heavily involved in DNA repair and cell repair; responsible for turning certain genes on and off; and essential for maintaining neurotransmitter levels, for the proper functioning of the brain.

Why Is it Important?

NAD+ is essential to the creation of energy in the body and the regulation of pivotal cellular processes. Here’s why it’s so important, how it was discovered, and how you can get more of it.

Whatisnad Hero

NAD+, or nicotinamide adenine dinucleotide, is a critical coenzyme found in every cell in your body, and it’s involved in hundreds of metabolic processes. But NAD+ levels decline with age. NAD+ has two general sets of reactions in the human body: helping turn nutrients into energy as a key player in metabolism and working as a helper molecule for proteins that regulate other cellular functions. These processes are incredibly important.

How NAD+ Is Powerful

Open any biology textbook and you’ll learn about NAD+, which stands for nicotinamide adenine dinucleotide. It’s a critical coenzyme found in every cell in your body that’s involved in hundreds of metabolic processes like cellular energy and mitochondrial health. NAD+ is hard at work in the cells of humans and other mammals, yeast and bacteria, even plants.

Scientists have known about NAD+ since it was first discovered in 1906, and since then our understanding of its importance has continued to evolve. For example, the NAD+ precursor niacin played a role in mitigating pellagra, a fatal disease that plagued the American south in the 1900s. Scientists at the time identified that milk and yeast, which both contain NAD+ precursors, alleviated symptoms. Over time scientists have identified several NAD+ precursors — including nicotinic acid, nicotinamide, and nicotinamide riboside, among others — which make use of natural pathways that lead to NAD+. Think of NAD+ precursors as different routes you can take to get to a destination. All the pathways get you to the same place but by different modes of transportation.

Recently, NAD+ has become a prized molecule in scientific research because of its central role in biological functions. The scientific community has been researching how NAD+ relates to notable benefits in animals that continue to inspire researchers to translate these findings to humans. So how exactly does NAD+ play such an important role? In short, it’s a coenzyme or “helper” molecule, binding to other enzymes to help cause reactions on the molecular level. But the body doesn’t have an endless supply of NAD+. In fact, it actually declines with age.

But the body doesn’t have an endless supply of NAD+. In fact, it actually declines with age. The history of NAD+ research, and its recent establishment in the science community, has opened the floodgates for scientists to investigate maintaining NAD+ levels and getting more NAD+.


Whatisnad Agedecline Artboard 1

What is the History of NAD+?

NAD+ was first identified Sir Arthur Harden and William John Young in 1906 when the two aimed to better understand fermentation — in which yeast metabolize sugar and create alcohol and CO2. It took nearly 20 years for more NAD+ recognition, when Harden shared the 1929 Nobel Prize in Chemistry with Hans von Euler-Chelpin for their work on fermentation. Euler-Chelpin identified that the structure of NAD+ is made up of two nucleotides, the building blocks for nucleic acids, which make up DNA. The finding that fermentation, a metabolic process, relied on NAD+ foreshadowed what we now know about NAD+ playing a critical role in metabolic processes in humans.

Euler-Chelpin, in his 1930 Nobel Prize speech, referred to NAD+ as cozymase, what it was once called, touting its vitality. “The reason for our doing so much work on the purification and determination of the constitution of this substance,” he said, “is that cozymase is one of the most widespread and biologically most important activators within the plant and animal world.”

Otto Heinrich Warburg — known for “the Warburg effect” — pushed the science forward in the 1930s, with research further explaining NAD+ playing a role in metabolic reactions. In 1931, the chemists Conrad A. Elvehjem and C.K. Koehn identified that nicotinic acid, a precursor to NAD+, was the mitigating factor in pellagra. United States Public Health Service Doctor Joseph Goldberger had previously identified that the fatal disease was connected to something missing in the diet, which he then called PPF for “pellagra preventive factor.” Goldberger died before the ultimate discovery that it was nicotinic acid, but his contributions led to the discovery, which also informed eventual legislation mandating the fortification of flours and rice on an international scale.

The next decade, Arthur Kornberg, who later won the Nobel Prize for showing how DNA and RNA are formed, discovered NAD synthetase, the enzyme that makes NAD+. This research marked the beginning of understanding the building blocks of NAD+. In 1958, the scientists Jack Preiss and Philip Handler defined what’s now known as the Preiss-Handler pathway. The pathway shows how nicotinic acid — the same form of vitamin B3 that helped cure pellagra — becomes NAD+. This helped scientists further understand the role of NAD+ in the diet. Handler later earned the National Medal of Science from President Ronald Reagan, who cited Handler’s “outstanding contributions to biomedical research…furthering the state of American science.”

While scientists had now realized the importance of NAD+, they had yet to discover its intricate impact on a cellular level. Forthcoming technologies in scientific research combined with comprehensive recognition of the coenzyme’s importance ultimately encouraged scientists to continue studying the molecule.

The Nuance of NAD+

Our current understanding of the importance of NAD+ really began in the 1960s. Using nuclear extracts from hen liver, French scientist Pierre Chambon identified a process called Poly ADP-ribosylation, where NAD+ is broken down into two component parts, one of which (nicotinamide) gets recycled, while the other (ADP-ribose) meets up with a protein. This research formed the foundation of the field of PARPs, or poly (ADP-ribose) polymerases, a group of proteins that rely on NAD+ to function and perform cellular functions. PARPs are similar to another group of proteins called sirtuins in that they both only function in the presence of NAD+.

Scientists often refer to sirtuins as “guardians of the genome” for their role in regulating cellular homeostasis. Homeostasis involves keeping the cell in balance. Sirtuins are a group of proteins that were first discovered in the 1970s but their dependence on NAD+ wasn’t realized until the 1990s. MIT biologist Leonard Guarente identified that SIR2, a sirtuin in yeast, extended the life of the yeast only when it was activated by NAD+.

“Without NAD+, SIR2 does nothing. That was the critical finding on the arc of sirtuin biology,” Guarente said.

Knowing this created a clear link between sirtuins and metabolism. It also clued scientists in on a crosstalk between biological functions, i.e., that metabolism is intricately related to other biological processes. Additionally, it inspired more research on a topic previously overlooked.

“There are maybe 12,000 papers on sirtuins now. At the time we discovered the NAD+ dependent deacetylase activity the number of papers was in the 100s,” Guarante’s said.

Humans get NAD+ from their diet via foods, however NAD+ is not absorbed orally and must be taken as an IV or Nasal Spray such as with NeuroNAD™ Nasal Spray, historically.

Dr Lieurance worked toward creating a better NAD+ delivery and shortly after pioneering the Nasal Delivery in 2018, he began working on way to make NAD+ stable in a suppository thus NeuroNAD™ Suppository was born after discovering. NeuroNAD™ Suppository combines ABC’s SRT™ Slow Release Technology along with Nano Lipospheric Technology NLT NAD+™. Both NeuroNAD™ products are a highly efficient way to boost NAD+ into he body and can be used together for maximum effect to raise levels.

NeuroNAD™ Suppository and NeuroNAD™ Nasal Spray can be taken together for an even more potent NAD+ replenishment program.The Heart and Brain and the most sensitive to low NAD+ levels. NeuroNAD™ Suppository uses the portal vein to absorb NAD+ directly into the blood stream which circulates directly intl the heart where NeuroNAD™ Nasal Spray is absorbed directly into brain through the nasal mucous. These two routes are the most superior routes next to IV which costs between $500-1500 per IV and the IV’s last 5-8 hours each. NeuroNAD™ Suppository should be taken at night before bed and NeuroNAD™ Nasal Spray should be taken during the daytime 1-4 times a day for a effective boost into the brain where is is most needed!

 

Disclaimer

Disclaimer

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent disease or medical conditions. The products and information found on Glutagenic.com are not intended to replace professional medical advice or treatment. Individual results may vary. Glutagenic urges you to seek the advice of a qualified professional for any health concern, and to share with your provider any information pertaining to your health and well-being, including the use of supplemental nutrition. We try our best not to make mistakes; however, if typographical errors appear in our site, we cannot be held responsible. All information presented here is not meant as a substitute for or alternative to information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice. <strong>*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.</strong>

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